蔡爽
2020-07-06 15:13:37 来源: 浏览:

材料学博士,湖北襄阳人,199108月出生,生物与医药硕士学导师。四川大学国家生物医学材料工程技术研究中心博士毕业,20186月被湖北文理学院以A类优秀博士全职引进。2023入选襄阳市隆中青年英才项目自然科学、工程技术类人才。

一、研究方向

1、多功能增透膜的制备:主要从事无模板的溶胶-凝胶法制备多功能增透膜,并对膜层内部粒子的生长机理和膜层表界面性质进行相关探索。

2、超顺磁性纳米粒子功能化:从事超顺磁性纳米粒子的制备、技术优化及表面多功能化方面的初步研究工作,实现了生物活性分子的分离;构建具有环境响应的磁性纳米载体材料实现抗肿瘤药物的可控释放。

二、科研项目

1、国家自然科学基金青年项目(32001009):基于Janus超顺磁性纳米粒子构建的叶酸/磁双重靶向功能外泌体药物递送系统的研究。24万,在研,主持

2、湖北省自然科学基金创新发展联合基金项目(2022CFD113):基于磁性纳米酶的外泌体靶向递送系统用于肿瘤的协同治疗的研究。5万,在研,主持

3、湖北省自然科学基金青年项目(2019CFB234):Janus超顺磁性纳米粒子的可控构筑及其对外泌体高效分离与双靶向修饰的研究。5万,结题,主持

4、湖北省教育厅中青年人才项目(Q20192602):基于碱/酸两步催化的溶胶凝胶法制备多功能增透膜及其机理研究。2万,结题,主持

5、湖北文理学院教师科研能力培育项目(2019kypgp001):基于Janus超顺磁性纳米粒子构建的叶酸/磁双重靶向功能外泌体药物递送系统的研究。5万,结题,主持

6、湖北文理学院A类博士科研启动项目(2059032):超顺磁性纳米粒子的可控构筑及其对外泌体高效特异性分离。30万,在研,主持。

7、襄阳甘田新材料科技有限公司技术委托项目:一种造纸颜料用疏水高分散高吸附二氧化硅及其制备方法与流程。2万,在研,主持

8、国家自然科学面上项目(31771037):磁性分级多孔纳米MOF复合材料的可控构筑及其对磷酸化蛋白/肽段的高效检测。62万元,在研参与

9、国家自然科学面上项目(51673124):基于磁性发光MOF纳米复合材料构筑循环肿瘤细胞的高效程序化逐级分离系统的研究。61万元结题参与

三、代表性论文

[1] Mengmeng Sun‡a, Kaixin Pu‡a, Xingrong Haoa, Tao Liu b, Zhiwei Lua, Gehong Sua, Chun Wua, Yanying Wanga, Shuang Caic*, Xiaoqing Zhaoa* and Hanbing Raoa*. Reasonable construction of a bimetallic organic framework MIL-88B (Fe, Ni) nanoenzyme based on deep learning assisted doxycycline hydrochloride and methyloxytetracycline hydrochloride. Journal of Materials Chemistry C, 2024, 12(1): 221-231.

[2] Tang Mingwei, Xueren Fang, Bowen Li, Meng Xu, Haiyan Wang, and Shuang Cai*. Hydrophobic Modification of Wood Using Tetramethylcyclotetrasiloxane Polymers, 2022, 14(10), 2077.

[3] Cao Mengting, Mingwei Tang, Wensheng Lin, Zehao Ding, Shuang Cai*, Hanxian Chen, and Xinxiang Zhang. 2022. Facile Fabrication of Fluorine-Free, Anti-Icing, and Multifunctional Superhydrophobic Surface on Wood Substrates. Polymers. 2022, 14(10), 1953.

[4] Huiping Lin, Qingjian Hu, Tianyu Liao, Xinxiang Zhang , Wenbin Yang*, and Shuang Cai*, Highly Hydrophobic Cotton Fabrics Modified by Poly(methylhydrogen)siloxane and Fluorinated Olefin: Characterization and Applications. Polymers, 2020, 12(4):833.

[5] Longqiang Ye, Liang Jiang, Mengmeng Zhu, Yulu Zhang*, Shuang Cai*. Sol-gel preparation of fluorine-containing hydrophobic SiO2 coating by using trifluoroethanol as dispersant and modifier simultaneously. Results in Physics, 2020, 16,102934.

[6] Zhi-LinRen||, Shuang Cai||, YingYing Liu, YinQing Xie, DingYuan, MinLei, Ping He* and Long Wang*, C(sp2)–H Functionalization of Imidazole at the C2- and C4-Position via Palladium-Catalyzed Isocyanide Insertion Leading to Indeno[1,2-d]imidazole and Imidazo[1,2-a]indole Derivatives. Journal of Organic Chemistry. 2020, 85,11014−11024.  

[7] Shuang Cai, Bin Luo, Peipei Jiang, Xiaoxi Zhou, Fang Lan, Qiangying Yi* and Yao Wu*. Immuno-modified superparamagnetic nanoparticles via host-guest interactions for high-purity capture and mild release of exosomes. Nanoscale 10 (2018) 14280-14289.

[8] Shuang Cai, Bin Luo, Xiaohui Zhan, Xiaoxi Zhou, Fang Lan, Qiangying Yi* and Yao Wu*. PH-response superstructures prepared by the assembly of Fe3O4 amphipathic Janus nanoparticles. Regenerative Biomaterials, 2018 5(2018) 251-259. (SCI新收录,工程技术三区,影响因子3.6)

[9] Shuang Cai, Qinglan Xue, Bibo Xia, Jie Yang, Hai-bing Lv, Hong-wei Yan*, Bo Jiang*. Hydrophobic–oleophobic antireflective film with excellent optical property prepared by a imple sol–gel route. Materials Letters 156 (2015) 14-16.

[10] Shuang Cai, Yulu Zhang, Hongli Zhang, Hongwei Yan, Haibing Lv*, and Bo Jiang*. Sol–Gel Preparation of Hydrophobic Silica Antireflective Coatings with Low Refractive Index by Base/Acid Two-Step Catalysis. ACS Applied Materials & Interfaces, 6(2014) 11470-11475.

[11] Shuang Cai, Yu-lu Zhang, Hong-wei Yan, Hai-bing Lv* and Bo Jiang*. Preparation of Hydrophilic-Oleophobic Antireflective Coatings with High Transmittance. Advanced Mterials Reseach 1051 (2014) 81-84.

(2024年3月18日更新)

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